Photocatalytic degradation of COVID-19 related drug arbidol hydrochloride by Ti3C2 MXene/supramolecular g-C3N4 Schottky junction photocatalystArticle Published on 2022-12-012022-11-15 Journal: Chemosphere [Category] 치료제, [키워드] Affect antiviral drug Arbidol arbidol hydrochloride composed COVID-19 COVID-19 outbreak Degradation drug increasingly less mechanism pathway Photocatalytic degradatiion provide Result resulting Schottky junction SEM significantly superoxide radical Supramolecular g-C(3)N(4) TEM Ti(3)C(2). Toxicity Treatment [DOI] 10.1016/j.chemosphere.2022.136461 PMC 바로가기
Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in miceArticle Published on 2022-11-012022-11-15 Journal: Inflammation research : official journal of the Eu [Category] 유전자 메커니즘, 진단, [키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome alleviate Analysis Anti-inflammatory anti-inflammatory property anti-inflammatory response ARDS CFZ Clofazimine coronavirus disease COVID-19 Critical decrease disease Diseases distress down-regulate histological change hyperimmune response IL-1β immune IMPROVE increasingly Infectious disease Inflammatory information inhibit involved lipopolysaccharide LPS lung Lung injury Macrophage macrophages mechanism mice Molecular biology pathway pharmacological mechanism potential molecular profile proliferation protective effect Protein protein expression Proteomic analysis proteomics proteomics. Pulmonary edema Quantitative Signal transduction Signaling significantly survival rate syndrome therapeutic strategy TNF-α [DOI] 10.1007/s00011-022-01623-w PMC 바로가기
Performance and validation of an adaptable multiplex assay for detection of serologic response to SARS-CoV-2 infection or vaccinationArticle Published on 2022-11-012022-11-15 Journal: Journal of Immunological Methods [Category] SARS, 진단, 치료기술, 치료제, [키워드] Antibody Response Antigen antigenic target assays correlated COVID-19 IgG immune response increasingly Infection infection with SARS-CoV-2 measure measurement multiplex Multiplex assay nucleocapsid antigen performance platform Quantitative ranged RBD Receptor binding domain S1 and S2 SARS-CoV-2 SARS-COV-2 infection sensitivity serologic assay Serologic response Serology. specificity subunit vaccination Variation [DOI] 10.1016/j.jim.2022.113345 PMC 바로가기
Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severityReview article Published on 2022-11-012022-10-05 Journal: Gene [Category] SARS, 바이오마커, 변종, 유전자 메커니즘, [키워드] ACE1 ACE2 AGTR1 ApoE association Case-control CCR5 Clinical outcome contribute contributing to Control correlation country COVID-19 COVID-19 pandemic COVID-19 susceptibility Critical eligible Evidence exacerbated examined Factor Genes Genetic genetic determinant Genetic polymorphism Genetic variant greater Health Healthcare system Host host genetics human gene I/D identify IFITM3 implicated increased risk increasingly infected individual infected individuals Infection investigated magnitude manifestation Manifestations Meta-analysis meta-analysis mutations Patient performed polymorphism progression provide required Research rs2285666 SARS-CoV-2 severe COVID-19 severity Statistical power statistically significant susceptibility systematic review variant with COVID-19 [DOI] 10.1016/j.gene.2022.146790 [Article Type] Review article
Atezolizumab for the treatment of advanced recurrent basal cell carcinoma and urothelial carcinoma of bladder: a case reportArticle Published on 2022-10-312022-11-15 Journal: Journal of Medical Case Reports [Category] 진단, [키워드] Administered Advanced basal cell carcinoma atezolizumab bladder Bladder cancer Cancer cancers carried Case report Cell Checkpoint inhibitor chemotherapeutic agent clinician Comorbidity Complete Compliance complication of COVID-19 cumulative Definitive disease dose female histology hospital increasingly indicated Infection inhibitor knowledge lymph nodes Metastasis metastatic Metastatic muscle-invasive bladder cancer Patient PD-L1 PD-L1 inhibitor. positive progressed Radiotherapy reached receiving Side effects smoking synchronous the patient therapy transurethral resection treated Treatment tumors [DOI] 10.1186/s13256-022-03634-x PMC 바로가기
A Robust, Highly Multiplexed Mass Spectrometry Assay to Identify SARS-CoV-2 VariantsArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome Care characterized circulation Clinical studies collected coronavirus defined Delta demonstrated diagnostic diagnostic capability effort functional health system health systems identify increasingly Infection prevention Iota Laboratory MALDI-TOF mass molecular MOST multiplex New York City omicron Panel Patient Patient care polymorphism Population public health measures public health systems RNA robust RT-PCR SARS-CoV-2 SARS-CoV-2 lineage SARS-CoV-2 variant seeking sensitivity specificity specimen Spectrometry Surveillance target tested Transmissibility USA utility vaccination variant variant call variant panel. virus WGS while whole-genome sequencing [DOI] 10.1128/spectrum.01736-22 PMC 바로가기
Sensitivity analysis of rapid antigen tests for the Omicron SARS-CoV-2 variant detection from nasopharyngeal swab samples collected in Santiago of ChileArticle Published on 2022-10-202022-11-15 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Analysis Antigen circulation collected Contagion contagiousness COVID-19 COVID-19 pandemic decrease Detection sensitivity evaluate faster genomic greater Health authority highlight immune evasion increasingly indicate Infection limit Local Mutation nasopharyngeal swab sample NPSs omicron Omicron detection outbreak pandemic pandemic in Chile Patient predominant Prevent rapid antigen test rapid antigen test. RAT RATs reduce RT-PCR RT-qPCR SARS-CoV-2 SARS-CoV-2 variant sensitivity suggested tested the SARS-CoV-2 virus variant viral amplification Viral load viral loads Viral variants VoC [DOI] 10.3389/fpubh.2022.976875 PMC 바로가기
Genetic diversity and evolutionary convergence of cryptic SARS- CoV-2 lineages detected via wastewater sequencingArticle Published on 2022-10-142022-11-15 Journal: PLoS Pathogens [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, 치료제, [키워드] Alpha VOC amino acid substitution amplify approach Course effective Epidemiology genetic diversity greater increasingly Infection Lineage lineages majority mutated New York City occurred omicron over Patient RBD Receptor binding domain reservoirs residue resolved SARS- CoV-2 SARS-CoV-2 SARS-CoV-2 surveillance sequence Sequencing Spread substitutions the RBD USA variant viral lineage VoC wastewater while [DOI] 10.1371/journal.ppat.1010636 PMC 바로가기
The Spike-Stabilizing D614G Mutation Interacts with S1/S2 Cleavage Site Mutations To Promote the Infectious Potential of SARS-CoV-2 VariantsArticle Published on 2022-10-122022-11-16 Journal: Journal of Virology [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome addition association carried Cell cleavage cleavage site cleaved coronavirus D614G D614G mutation Delta dependent on epistasis epistatic interaction evaluate expressing expression increasingly Mutation omicron pandemic pathogenic Potential Protein proteolytic proteolytic cleavage pseudovirions pseudovirus pseudoviruses remained resulting S1 subunit S1/S2 S1/S2 cleavage S1/S2 cleavage site SARS-CoV-2 SARS-CoV-2 variant Site spike spike mutation spikes Spread stabilizing effect successive wave Transmissibility variant variants variants of concern variants. Viral particles viral spike viral variant virions wild-type Wuhan [DOI] 10.1128/jvi.01301-22 PMC 바로가기
Conservative treatment with mouthwashes followed by tongue photo biomodulation therapy in Covid-19: a case reportArticle Published on 2022-10-062022-11-15 Journal: Journal of Medical Case Reports [Category] 치료제, [키워드] 6 hours Antibiotics antivirals Case report conservative treatment coronavirus disease cough COVID-19 described geographic tongue Guidance had no increasingly indicated initial lesion lesions lidocaine manifestation medications Mild mouth mouth rinses mouthwashe nasal congestion oral oral manifestation oral manifestations Patient Photo biomodulation therapy positive promote Rash regimen repeated sense of taste sensitivity steroid Steroids subsequent Symptomatic treatment systemic Systemic rash. tested therapy tongue torso Treatment unique [DOI] 10.1186/s13256-022-03519-z PMC 바로가기